Coleus Forskohlii contains the compound forskolin which has been shown to be a potent intracellular cAMP (Cyclic Adenosine Monophosphate) elevator. Increased intracellular levels of cAMP are associated with: inhibition of platelet activating factor (PAF), mast cell degranulation, histamine release, relaxation of smooth muscle and arteries, and increased force of contraction in the heart muscle. Forskolin not only acts on cAMP. It also has inhibitory activity on membrane transport and channel proteins. One of the principal events of heart disease, strokes and peripheral vascular disease is the formation of thromboses. An initiating factor of these clots is the excess activation of PAF. PAF starts a cascade of events that result in clinical symptoms. Forskolin interferes with the binding of PAF to its binding sites.

Lutein and Zeaxanthin –There are over 500 naturally occurring carotenoids. Human blood contains between 7 and 20 of these carotenoids. The most abundant being beta-carotene, lutein, zeaxanthin, beta-cryptoxanthin, alpha-carotene and lycopene in that order. Epidemiological studies have shown an inverse relationship between carotenoid consumption and the development of some cancers and macular degeneration. Carotenoids are considered to be lipophilic antioxidant constituents of the blood.

Ginkgo Biloba is one of the oldest living tree species, dating back over 300 million years, and individual trees can live for over 1,000 years. In China, extracts of the fruit and leaves of the Ginkgo tree have been used for over 5,000 years to treat lung ailments, such as asthma and bronchitis, and as a remedy for cardiovascular diseases. Recently, western researchers have been studying Ginkgo Biloba as a treatment for senility, hardening of the arteries, and as a treatment for oxygen deprivation. More than 34 human studies on Ginkgo have been published since 1975, showing, among other things, that Ginkgo can increase the body’s production of the universal energy molecule adenosine triphosphate, commonly called ATP.